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important safety information

 

WHAT IS INVOKANA®?

  • INVOKANA® is a prescription medicine used along with diet and exercise to lower blood sugar in adults with type 2 diabetes.

  • INVOKANA® is not for people with type 1 diabetes.

  • INVOKANA® is not for people with diabetic ketoacidosis (increased ketones in blood or urine).

  • It is not known if INVOKANA® is safe and effective in children under 18 years of age.

IMPORTANT SAFETY INFORMATION
WHAT IS THE MOST IMPORTANT INFORMATION I SHOULD KNOW ABOUT INVOKANA®?

INVOKANA® can cause important side effects, including:

  • Dehydration. INVOKANA® can cause some people to have dehydration (the loss of body water and salt). Dehydration may cause you to feel dizzy, faint, lightheaded, or weak, especially when you stand up (orthostatic hypotension).

    You may be at higher risk of dehydration if you:

    • have low blood pressure

    • take medicines to lower your blood pressure, including diuretics (water pill)

    • are on low sodium (salt) diet

    • have kidney problems

    • are 65 years of age or older

  • Vaginal yeast infection. Women who take INVOKANA® may get vaginal yeast infections. Symptoms of a vaginal yeast infection include:

    • vaginal odor

    • white or yellowish vaginal discharge (discharge may be lumpy or look like cottage cheese)

    • vaginal itching

  • Yeast infection of the penis (balanitis or balanoposthitis). Men who take INVOKANA® may get a yeast infection of the skin around the penis. Certain men who are not circumcised may have swelling of the penis that makes it difficult to pull back the skin around the tip of the penis. Other symptoms of yeast infection of the penis include:

    • redness, itching, or swelling of the penis

    • rash of the penis

    • foul smelling discharge from the penis

    • pain in the skin around penis

Talk to your doctor about what to do if you get symptoms of a yeast infection of the vagina or penis. Your doctor may suggest you use an over-the-counter antifungal medicine. Talk to your doctor right away if you use an over-the-counter antifungal medication and your symptoms do not go away.

WHO SHOULD NOT TAKE INVOKANA®?

Do not take INVOKANA® if you:

  • are allergic to canagliflozin or any of the ingredients in INVOKANA®. See the end of the Medication Guide for a list of ingredients in INVOKANA®. Symptoms of allergic reaction to INVOKANA® may include:

    • rash

    • raised red patches on your skin (hives)

    • swelling of the face, lips, tongue, and throat that may cause difficulty in breathing or swallowing

  • have severe kidney problems or are on dialysis

WHAT SHOULD I TELL MY DOCTOR BEFORE TAKING INVOKANA®?

Before you take INVOKANA®, tell your doctor if you:

  • have kidney problems

  • have liver problems

  • are on a low sodium (salt) diet. Your doctor may change your diet or your dose of INVOKANA®.

  • have ever had an allergic reaction to INVOKANA®

  • have other medical conditions

  • are pregnant or plan to become pregnant. It is not known if INVOKANA® will harm your unborn baby. If you are pregnant, talk with your doctor about the best way to control your blood sugar while you are pregnant.

  • are breastfeeding or plan to breastfeed. It is not known if INVOKANA® passes into your breast milk. Talk with your doctor about the best way to feed your baby if you are taking INVOKANA®.

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.

 

INVOKANA® may affect the way other medicines work, and other medicines may affect how INVOKANA® works.
Especially tell your doctor if you take:

  • diuretics (water pills)

  • rifampin (used to treat or prevent tuberculosis)

  • phenytoin or phenobarbital (used to control seizures)

  • ritonavir (Norvir®, Kaletra®, Lopinavir®) (used to treat HIV infection)

  • digoxin (Lanoxin®) (used to treat heart problems)

Ask your doctor or pharmacist for a list of these medicines if you are not sure if your medicine is listed above.

Know the medicines you take. Keep a list of them and show it to your doctor and pharmacist when you get a new medicine.

HOW SHOULD I TAKE INVOKANA®?
  • Take INVOKANA® by mouth 1 time each day exactly as your doctor tells you to take it.

  • Your doctor will tell you how much INVOKANA® to take and when to take it. Your doctor may change your dose if needed.

  • It is best to take INVOKANA® before the first meal of the day.

  • Your doctor may tell you to take INVOKANA® along with other diabetes medicines. Low blood sugar can happen more often when INVOKANA® is taken with certain other diabetes medicines. See “What are the possible side effects of INVOKANA®?”

  • If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take two doses of INVOKANA® at the same time. Talk to your doctor if you have questions about a missed dose.

  • If you take too much INVOKANA®, call your doctor or go to the nearest hospital emergency room right away.

  • When your body is under some types of stress, such as fever, trauma (such as a car accident), infection, or surgery, the amount of diabetes medicine you need may change. Tell your doctor right away if you have any of these conditions and follow your doctor’s instructions.

  • Stay on your prescribed diet and exercise program while taking INVOKANA®.

  • Check your blood sugar as your doctor tells you to.

  • INVOKANA® will cause your urine to test positive for glucose.

  • Your doctor may do certain blood tests before you start INVOKANA® and during treatment as needed. Your doctor may change your dose of INVOKANA® based on the results of your blood tests.

  • Your doctor will check your diabetes with regular blood tests, including your blood sugar levels and your hemoglobin A1C.

WHAT ARE THE POSSIBLE SIDE EFFECTS OF INVOKANA®?

INVOKANA® may cause serious side effects, including:

See "What is the most important information I should know about INVOKANA®?"

  • kidney problems

  • a high amount of potassium in your blood (hyperkalemia)

  • low blood sugar (hypoglycemia). If you take INVOKANA® with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin, your risk of getting low blood sugar is higher. The dose of your sulfonylurea medicine or insulin may need to be lowered while you take INVOKANA®.

Signs and symptoms of low blood sugar may include:

  • headache

  • drowsiness

  • weakness

  • dizziness

  • confusion

  • irritability

  • hunger

  • fast heartbeat

  • sweating

  • shaking or feeling jittery

  • serious allergic reaction. If you have any symptoms of a serious allergic reaction, stop taking INVOKANA® and call your doctor right away or go to the nearest hospital emergency room. See “Who should not take INVOKANA®?”. Your doctor may give you a medicine for your allergic reaction and prescribe a different medicine for your diabetes.

The most common side effects of INVOKANA® include:

  • vaginal yeast infections and yeast infections of the penis (See “What is the most important information I should know about INVOKANA®?”)

  • urinary tract infection

  • changes in urination, including urgent need to urinate more often, in larger amounts, or at night

Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of INVOKANA®. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

You may also report side effects to Janssen Scientific Affairs, LLC at 1-800-526-7736.

Please see full Product Information and Medication Guide.

Trademarks are those of their respective owners.

003182-130920

 

WHAT IS INVOKANA®?

  • INVOKANA® is a prescription medicine used along with diet and exercise to lower blood sugar in adults with type 2 diabetes.

  • INVOKANA® is not for people with type 1 diabetes.

  • INVOKANA® is not for people with diabetic ketoacidosis (increased ketones in blood or urine).

  • It is not known if INVOKANA® is safe and effective in children under 18 years of age.

IMPORTANT SAFETY INFORMATION
WHAT IS THE MOST IMPORTANT INFORMATION I SHOULD KNOW ABOUT INVOKANA®?

INVOKANA® can cause important side effects, including:

  • Dehydration. INVOKANA® can cause some people to have dehydration (the loss of body water and salt). Dehydration may cause you to feel dizzy, faint, lightheaded, or weak, especially when you stand up (orthostatic hypotension).

    You may be at higher risk of dehydration if you:

    • have low blood pressure

    • take medicines to lower your blood pressure, including diuretics (water pill)

    • are on low sodium (salt) diet

    • have kidney problems

    • are 65 years of age or older

  • Vaginal yeast infection. Women who take INVOKANA® may get vaginal yeast infections. Symptoms of a vaginal yeast infection include:

    • vaginal odor

    • white or yellowish vaginal discharge (discharge may be lumpy or look like cottage cheese)

    • vaginal itching

  • Yeast infection of the penis (balanitis or balanoposthitis). Men who take INVOKANA® may get a yeast infection of the skin around the penis. Certain men who are not circumcised may have swelling of the penis that makes it difficult to pull back the skin around the tip of the penis. Other symptoms of yeast infection of the penis include:

    • redness, itching, or swelling of the penis

    • rash of the penis

    • foul smelling discharge from the penis

    • pain in the skin around penis

Talk to your doctor about what to do if you get symptoms of a yeast infection of the vagina or penis. Your doctor may suggest you use an over-the-counter antifungal medicine. Talk to your doctor right away if you use an over-the-counter antifungal medication and your symptoms do not go away.

WHO SHOULD NOT TAKE INVOKANA®?

Do not take INVOKANA® if you:

  • are allergic to canagliflozin or any of the ingredients in INVOKANA®. See the end of the Medication Guide for a list of ingredients in INVOKANA®. Symptoms of allergic reaction to INVOKANA® may include:

    • rash

    • raised red patches on your skin (hives)

    • swelling of the face, lips, tongue, and throat that may cause difficulty in breathing or swallowing

  • have severe kidney problems or are on dialysis

WHAT SHOULD I TELL MY DOCTOR BEFORE TAKING INVOKANA®?

Before you take INVOKANA®, tell your doctor if you:

  • have kidney problems

  • have liver problems

  • are on a low sodium (salt) diet. Your doctor may change your diet or your dose of INVOKANA®.

  • have ever had an allergic reaction to INVOKANA®

  • have other medical conditions

  • are pregnant or plan to become pregnant. It is not known if INVOKANA® will harm your unborn baby. If you are pregnant, talk with your doctor about the best way to control your blood sugar while you are pregnant.

  • are breastfeeding or plan to breastfeed. It is not known if INVOKANA® passes into your breast milk. Talk with your doctor about the best way to feed your baby if you are taking INVOKANA®.

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.

 

INVOKANA® may affect the way other medicines work, and other medicines may affect how INVOKANA® works.
Especially tell your doctor if you take:

  • diuretics (water pills)

  • rifampin (used to treat or prevent tuberculosis)

  • phenytoin or phenobarbital (used to control seizures)

  • ritonavir (Norvir®, Kaletra®, Lopinavir®) (used to treat HIV infection)

  • digoxin (Lanoxin®) (used to treat heart problems)

Ask your doctor or pharmacist for a list of these medicines if you are not sure if your medicine is listed above.

Know the medicines you take. Keep a list of them and show it to your doctor and pharmacist when you get a new medicine.

HOW SHOULD I TAKE INVOKANA®?
  • Take INVOKANA® by mouth 1 time each day exactly as your doctor tells you to take it.

  • Your doctor will tell you how much INVOKANA® to take and when to take it. Your doctor may change your dose if needed.

  • It is best to take INVOKANA® before the first meal of the day.

  • Your doctor may tell you to take INVOKANA® along with other diabetes medicines. Low blood sugar can happen more often when INVOKANA® is taken with certain other diabetes medicines. See “What are the possible side effects of INVOKANA®?”

  • If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take two doses of INVOKANA® at the same time. Talk to your doctor if you have questions about a missed dose.

  • If you take too much INVOKANA®, call your doctor or go to the nearest hospital emergency room right away.

  • When your body is under some types of stress, such as fever, trauma (such as a car accident), infection, or surgery, the amount of diabetes medicine you need may change. Tell your doctor right away if you have any of these conditions and follow your doctor’s instructions.

  • Stay on your prescribed diet and exercise program while taking INVOKANA®.

  • Check your blood sugar as your doctor tells you to.

  • INVOKANA® will cause your urine to test positive for glucose.

  • Your doctor may do certain blood tests before you start INVOKANA® and during treatment as needed. Your doctor may change your dose of INVOKANA® based on the results of your blood tests.

  • Your doctor will check your diabetes with regular blood tests, including your blood sugar levels and your hemoglobin A1C.

WHAT ARE THE POSSIBLE SIDE EFFECTS OF INVOKANA®?

INVOKANA® may cause serious side effects, including:

See "What is the most important information I should know about INVOKANA®?"

  • kidney problems

  • a high amount of potassium in your blood (hyperkalemia)

  • low blood sugar (hypoglycemia). If you take INVOKANA® with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin, your risk of getting low blood sugar is higher. The dose of your sulfonylurea medicine or insulin may need to be lowered while you take INVOKANA®.

Signs and symptoms of low blood sugar may include:

  • headache

  • drowsiness

  • weakness

  • dizziness

  • confusion

  • irritability

  • hunger

  • fast heartbeat

  • sweating

  • shaking or feeling jittery

  • serious allergic reaction. If you have any symptoms of a serious allergic reaction, stop taking INVOKANA® and call your doctor right away or go to the nearest hospital emergency room. See “Who should not take INVOKANA®?”. Your doctor may give you a medicine for your allergic reaction and prescribe a different medicine for your diabetes.

The most common side effects of INVOKANA® include:

  • vaginal yeast infections and yeast infections of the penis (See “What is the most important information I should know about INVOKANA®?”)

  • urinary tract infection

  • changes in urination, including urgent need to urinate more often, in larger amounts, or at night

Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of INVOKANA®. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

You may also report side effects to Janssen Scientific Affairs, LLC at 1-800-526-7736.

Please see full Product Information and Medication Guide.

Trademarks are those of their respective owners.

003182-130920

 

 
 
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Oops. We're sorry. There seems to be a technical error on our side. Please call 1-877-INVOKANA (1-877-468-6526) for further assistance,
or check back here soon.

However, you have been successfully enrolled in the INVOKANA® CarePath™ support program.

 
 
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you are enrolled!

Oops. We're sorry. There seems to be a technical error on our side. Please call 1-877-INVOKANA (1-877-468-6526) for further assistance,
or check back here soon.

 
 
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you are enrolled!

You have been successfully enrolled in the INVOKANA® CarePath™ support program. We've sent you a message for your records.

 
 
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you are enrolled!

You have been successfully enrolled in the INVOKANA® CarePath™ support program. We've sent you a message for your records.

 
 
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We’re sorry. Based on your answers, you’re ineligible for the Savings Card Program. But you can still register for INVOKANA® CarePath™—click here. If you have questions about eligibility, please call INVOKANA® CarePath™ at 1-877-INVOKANA (1-877-468-6526).

 
 
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get started on INVOKANA® CarePath!
we're here to support you on your journey with
INVOKANA® (canagliflozin).

 
 
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get started on INVOKANA® CarePath™!
we're here to support you on your journey with
INVOKANA®(canagliflozin).

 
 

your savings card is activated!

You have been successfully enrolled in the INVOKANA® CarePath™ support program.
Your card has been activated. We've sent you a message for your records.

If you do not have a card:
 
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You can begin using this activated card immediately. Use your INVOKANA® CarePath Savings Card at your pharmacy to receive instant savings off your prescription costs for INVOKANA® (canagliflozin).

  • This offer may not be combined with any other coupon, discount, prescription savings card, free trial, or other offer. The selling, purchasing, trading, or counterfeiting of this card is prohibited. Offer good only in the US and Puerto Rico. Janssen Pharmaceuticals, Inc., reserves the right to rescind, revoke, or amend this offer without notice at any time.
  • Void where prohibited, taxed, or otherwise restricted by law.
  • Offer for new enrollment expires December 31, 2014. Each patient can only enroll in this program once.
  • If you would like to opt out of the program at any time, please call 1-877-INVOKANA (1-877-468-6526).
Not available to individuals enrolled in federally subsidized healthcare programs that cover prescription drugs, including Medicare, Medicaid, TRICARE, or any similar federal or state programs. As a condition of participating in this program, you must ensure that you comply with any co-payment disclosure requirements of your insurance carrier or third-party payer, including, if required, disclosing to your insurer the amount of co-payment support you receive from this program.
 
 
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Thank you for joining our mailing list.

 

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you are enrolled!

You have been successfully enrolled in the INVOKANA® CarePath™ support program. We've sent you a message for your records.

 
 
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Your savings card is activated!

You have been successfully enrolled in the INVOKANA® CarePath support program. Your card has been activated. We’ve sent you a message for your records.

If you do not have a card:

PRINT NOW
 

You can begin using this activated card immediately. Use your INVOKANA® CarePath Instant Savings Card at your pharmacy to receive instant
savings off your prescription costs for INVOKANA® (canagliflozin).

  • This offer may not be combined with any other coupon, discount, prescription savings card, free trial, or other offer. The selling, purchasing, trading, or counterfeiting of this card is prohibited. Offer good only in the US and Puerto Rico. Janssen Pharmaceuticals, Inc., reserves the right to rescind, revoke, or amend this offer without notice at any time.
  • Void where prohibited, taxed, or otherwise restricted by law.
  • Offer for new enrollment expires April 1, 2013. Each patient can only enroll in this program once.
  • If you would like to opt out of the program at any time, please call 1-877-INVOKANA® (1-877-468-6526).

Not available to individuals enrolled in federally subsidized healthcare programs that cover prescription drugs, including Medicare, Medicaid, TRICARE
or any similar federal or state programs. As a condition of participating in this program, you must ensure that you comply with any copayment disclosure
requirements of your insurance carrier or third-party payor, including, if required, disclosing to your insurer the amount of copayment support you receive
from this program.

 
 
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Enroll new Savingcard!

Congratulations! Your card has been activated.

 
 
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INVOKANA® CarePath is a support program
for patients with type 2 diabetes. Please visit
our website for healthcare providers.

 
 
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We're sorry. Based on your answers, you're ineligible for the INVOKANA® CarePath™ Savings Card. However, you have been successfully enrolled
in the INVOKANA® CarePath™ support program. We've sent you a message for your records.

 
 
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Oops. We're sorry. There was an error activating your INVOKANA® CarePath™ Savings Card. Please call 1-877-INVOKANA (1-877-468-6526)
for assistance activating your card.

However, you have been successfully enrolled in the INVOKANA® CarePath™ support program.

 

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